Effects of dietary clinoptilolite on reproductive performance, serum progesterone and insulin-like growth factor-1 concentrations in dairy cows during pregnancy and lactation

The objective of this study was to evaluate the effects dietary zeolite clinoptilolite on re- productive performance, serum progesterone and insulin-like growth factor 1 (IGF-1) concentra- tions in 78 Holstein Friesian (HF) cows during pregnancy lactation. were divided into two groups comprising 40 (control group; CON) 38 (CPL group) cows. To assess repro- ductive performance HF following variables registered: interval from calv- ing first insemination (days open service, DFS), calving pregnancy, DOP), number services per (NSP). average values (5.64±0.59 ng/mL vs. 5.16±0.64 ng/mL) not statistically different (p⟨0.05) IGF-1 levels (400.17±17.72 348.36±20.39 higher CON than CPL group which received 50 g twice a day. However, ovarian cyclity resumed days 60 postpartum. In addition, DFS DOP (p>0.05) shorter (115.1±19.9 137.5±36.3 124.2±17.3 143.8±33.5 days, respectively). During 305 lactation, milk production (8325.5±628.8 kg 8050±586.8 kg). NSP lower (1.91 2.14). supplement had positive in- fluence yield, exhibited modulating endocrine status dairy cows, im- proved reproductive with decreased NSP, fewer DOP.